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Allele : Grik1<tm1Sfh> glutamate receptor, ionotropic, kainate 1; targeted mutation 1, Stephen F Heinemann

Primary Identifier  MGI:2176347 Allele Type  Targeted
Attribute String  Null/knockout Gene  Grik1
Transmission  Germline Strain of Origin  129S/SvEv-Gpi1<c>
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance cassette replaced a 345 bp genomic fragment that contains sequences encoding the membrane I domain required for protein function. Physiological assays on dorsal root ganglion cells of homozygous mice confirmed that no functional receptor was made from this allele.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • GluR5 KO,
  • GluR5 KO,
  • GluR5-,
  • GluR5-,
  • GLUK5-,
  • GLUK5-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

37 Publication categories