Primary Identifier | MGI:2176476 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Efnb2 |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The targeting strategy involved deleting the signal sequence and fusing a tau-lacZ PGK-neomycin cassette in frame with the initiation codon. There was no expression of endogenous mRNA by in situ hybridization in homozygous mutant animals. Heterozygous embryos expressed beta-galactosidase in a pattern that was indistinguishable from the endogenous expression pattern. |