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Allele : E2f3<tm1.2Gle> E2F transcription factor 3; targeted mutation 1.2, Gustavo Leone

Primary Identifier	MGI:2177428	Allele Type	Targeted
Attribute String	Null/knockout	Gene	E2f3
Transmission	Germline	Strain of Origin	129P2/OlaHsd
Is Recombinase	false	Is Wild Type	false

molecularNote

A floxed neomycin resistance cassette was inserted upstream of exon 3 and an additional loxP site was inserted downstream of the exon. Transient expression of Cre recombinase in ES cells excised both the neo cassette and exon 3.

mutations:
Intragenic deletion

cellLines:
Not Specified

synonyms:
E2F3-,
E2F3-

earliestPublication:
Wu L, et al. (2001) The E2F1-3 transcription factors are essential for cellular proliferation. Nature 414(6862):457-62

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

14 Publication categories

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