| Primary Identifier | MGI:2177831 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Mapk14 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | An internal 2 kb genomic fragment was replaced with a lacZ gene and a PGK-neomycin cassette. The deleted region contains two exons encoding amino acids 40-103, which includes most of the amino-terminal lobe of the catalytic domain including the glycine-rich ATP binding loop. Western blot analysis of lysates prepared from E10.5 embryos confirmed that no detectable protein was expressed from this allele. |
