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Allele : Ptpn1<tm1Bpk> protein tyrosine phosphatase, non-receptor type 1; targeted mutation 1, Brian P Kennedy

Primary Identifier  MGI:2176520 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ptpn1
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette replaced a genomic fragment containing exons 5 and 6, which contain sequences encoding the tyrosine phospahatase active site. Western blot analysis on liver microsomes derived from homozygous mice confirmed that no detectable protein was expressed from this allele.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • PTP-1B -,
  • PTP1B-KO,
  • PTP1B-KO,
  • PTP-1B -
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

35 Publication categories