Primary Identifier | MGI:2176538 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Efnb2 |
Inheritance Mode | Recessive | Transmission | Germline |
Strain of Origin | 129S7/SvEvBrd-Hprt1<+> | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A loxP site was inserted 45 bp upstream in the 5' UTR and a floxed PGKneo cassette was inserted downstream of the first exon. The floxed PGKneo cassette was removed by transient Cre expression in the ES cells which resulted in a floxed intact exon I. |