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Allele : Selplg<tm1Fur> selectin, platelet (p-selectin) ligand; targeted mutation 1, Bruce Furie

Primary Identifier  MGI:2176571 Allele Type  Targeted
Attribute String  Null/knockout Gene  Selplg
Transmission  Germline Strain of Origin  STOCK 129/Sv and C57BL/6J and SJL
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance cassette replaced a small DNA segment of the coding region (+69 to 94). A 300 bp segment in the 5' flanking region containing CT repeats was also deleted. Northern blot analysis on thymus and spleen RNA from homozygous mice demonstrated that no detecable transcript was produced from this allele. Flow cytometry experiments on leukocytes derived from homozygous mice confirmed that no detectable cell surface protein was expressed from this allele.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • PSGL-1-,
  • PSGL-1-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

59 Publication categories