Primary Identifier | MGI:2177923 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Eif4ebp1 |
Transmission | Germline | Strain of Origin | 129S4/SvJae |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The splice acceptor site and the first 57 nucleotides of exon 2 were replaced with the neomycin-resistance gene. The disrupted portion of exon 2 encodes amino acids 47 to 66, which encompasses the binding site for EIF4E. |