| Primary Identifier | MGI:2177948 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | F2 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | An HPRT minigene replaced a genomic fragment containing exons 1 and 2, which encode the signal peptide and pro-peptide. Northern blot analysis on liver RNA derived from homozygous mice demonstrated that no detectable transcript was produced from this allele. Western blot analysis on liver extracts derived from plasma of homozygous mice confirmed that no protein was expressed from this allele. |
