| Primary Identifier | MGI:2177294 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Amelx |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A neomycin selection cassette replaced 300 bp of exon 2/intron 2 including the translation start site. RT-PCR analysis on tooth germ isolated from homozygous mice demonstrated that a aberrant transcript was produced from this allele that spliced exon 1 to exon 3. However, protein analysis and western blot experiments confirmed that no detectable protein was expressed from this allele. |
