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Allele : Cftr<tm3Hgu> cystic fibrosis transmembrane conductance regulator; targeted mutation 3, MRC Human Genetics Unit
Primary Identifier  MGI:2177540 Allele Type  Targeted
Attribute String  Humanized sequence, Hypomorph Gene  Cftr
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A mutation was created in exon 12 that changed codon 551 from glycine to aspartate (p.G551D). In addition, two tandem copies of a neomycin resistance cassette were inserted into intron 12b.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • p.G551D,
  • cftr<TgHm1G551D>,
  • cftr<G551D>,
  • p.G551D,
  • cftr<G551D>,
  • cftr<TgHm1G551D>,
  • Cftr<tm1G551D>,
  • Cftr<tm1G551D>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

11 Publication categories





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