| Primary Identifier | MGI:2177703 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Gck |
| Transmission | Germline | Strain of Origin | 129X1/SvJ |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A neomycin selection cassette was inserted into exon 1beta, which contains the promoter for the pancreatic-specific isoform of the gene. Glucose phosphorylation assays on samples derived from pancreatic islets and liver tissue of homozygous mice confirmed that no functional protein was expressed in the pancreas, but liver expression was unaffected. |
