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Allele : Gck<tm1.1Mgn> glucokinase; targeted mutation 1.1, Mark A Magnuson

Primary Identifier	MGI:2177709	Allele Type	Targeted
Attribute String	Conditional ready, No functional change	Gene	Gck
Transmission	Germline	Strain of Origin	129S6/SvEvTac
Is Recombinase	false	Is Wild Type	false

molecularNote

This allele is a derivative of Gck^tm1Mgn in which the loxP flanked neomycin selection cassette was removed in ES cells by transient Cre expression prior to the production of chimeric mice.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
gk<lox>,
gk<lox>

earliestPublication:
Postic C, et al. (1999) Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase. J Biol Chem 274(1):305-15

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

2 Carried By

0 Driven By

10 Publication categories

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