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Allele : Evx1<tm1Mrc> even-skipped homeobox 1; targeted mutation 1, Mario R Capecchi

Primary Identifier  MGI:2177782 Allele Type  Targeted
Attribute String  Null/knockout Gene  Evx1
Transmission  Germline Strain of Origin  129S7/SvEvBrd
Is Recombinase  false Is Wild Type  false
description 

These mice have a second closely linked mutation that is thought to underlie the observed early embryonic lethality, and therefore it may not be due to the Evx1 mutation. See the discussion in the following reference: J:70192.

molecularNote  A neomycin resistance cassette replaced a DNA segment coding for the first amino acid residues of the first helix of the homeobox domain and part of intron 2.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • evx1<->,
  • evx1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories