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Allele : Tcf3<tm1Cmu> transcription factor 3; targeted mutation 1, Cornelis Murre

Primary Identifier  MGI:2178119 Allele Type  Targeted
Attribute String  Null/knockout Gene  Tcf3
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
description  ES cell line = either E14 or E14-derived.
molecularNote  Insertion of a neomycin resistance cassette into the E12-specific exon disrupted the gene. RT-PCR studies of fetal liver and of lung from 5 week old mice detected trace amounts of E47-specific transcript in homozygous mutant mice. The authors predict that both gene products, E12 and E47, are inactivated in this allele.
  • mutations:
  • Insertion
  • synonyms:
  • E2A-,
  • E2A-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

19 Publication categories