| First Author | Thanos PK | Year | 2010 |
| Journal | Behav Brain Res | Volume | 207 |
| Issue | 2 | Pages | 508-11 |
| PubMed ID | 19853629 | Mgi Jnum | J:156902 |
| Mgi Id | MGI:4421641 | Doi | 10.1016/j.bbr.2009.10.020 |
| Citation | Thanos PK, et al. (2010) Dopamine D4 receptor (D4R) deletion in mice does not affect operant responding for food or cocaine. Behav Brain Res 207(2):508-11 |
| abstractText | In this study we examined the genetic contribution of the D4R in food and cocaine self-administration using D4R mice. Mice were examined for operant responding to food pellets or intravenous cocaine. Compared to wild-type mice (D4R(+/+)), both heterozygous (D4R(+/-)) and knockout (D4R(-/-)) mice showed no difference in responding for food or cocaine. Our findings suggest that the D4R is not directly involved in mediating operant response behaviors for food or cocaine. |
