First Author | Wright N | Year | 2008 |
Journal | Nat Neurosci | Volume | 11 |
Issue | 10 | Pages | 1140-2 |
PubMed ID | 18776896 | Mgi Jnum | J:141146 |
Mgi Id | MGI:3817344 | Doi | 10.1038/nn.2188 |
Citation | Wright N, et al. (2008) Laminar analysis of the role of GluR1 in experience-dependent and synaptic depression in barrel cortex. Nat Neurosci 11(10):1140-2 |
abstractText | Several synaptic depression mechanisms have been described for the hippocampus, cerebellum and neocortex in vitro, but little is known about which, if any, are engaged during experience-dependent depression (EDD). We found that EDD in the mouse barrel cortex depends on the AMPA subunit GluR1 in layers II/III and IV, but not in layer V, and that long-term depression is also GluR1 dependent in the IV-II/III, but not II/III-V, pathway. |