| First Author | Taylor AM | Year | 2011 |
| Journal | Behav Brain Res | Volume | 224 |
| Issue | 1 | Pages | 8-14 |
| PubMed ID | 21641937 | Mgi Jnum | J:176997 |
| Mgi Id | MGI:5293281 | Doi | 10.1016/j.bbr.2011.05.016 |
| Citation | Taylor AM, et al. (2011) Dissociations within short-term memory in GluA1 AMPA receptor subunit knockout mice. Behav Brain Res 224(1):8-14 |
| abstractText | GluA1 AMPA receptor subunit knockout mice display a selective impairment on short-term recognition memory tasks. In this study we tested whether GluA1 is important for short-term memory that is necessary for bridging the discontiguity between cues in trace conditioning. GluA1 knockout mice were not impaired at using short-term memory traces of T-maze floor inserts, made of different materials, to bridge the temporal gap between conditioned stimuli and reinforcement during appetitive discrimination tasks. Thus, different aspects of short-term memory are differentially sensitive to GluA1 deletion. This dissociation may reflect processing of qualitatively different short-term memory traces. Memory that results in performance of short-term recognition (e.g. for objects or places) may be different from the memory required for associative learning in trace conditioning. |
