| Primary Identifier | MGI:2178120 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Gria2 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The editing site complementary sequence (ECS) in intron 11 was replaced with a loxP-flanked neomycin resistance cassette. The neomycin cassette was removed by transient Cre expression in ES cells prior to the production of chimeric mice, leaving a single loxP site in place of the ECS. RT-PCR analysis on RNA derived from brains of homozygous mice demonstrated that unedited transcripts were produced from this allele. |
