Primary Identifier | MGI:2178143 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Tcf3 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
description | ES cell line was E14, or was E14-derived. |
molecularNote | Insertion of a neomycin resistance cassette into the E47-specific HLH exon disrupted the gene. Western blot analyses of thymus from homozygous mutant mice did not detect E47 protein, and detected E12 protein at levels that were at least 5-fold lower than wild-type. |