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Allele : Skp2<tm1Kin> S-phase kinase-associated protein 2; targeted mutation 1, Kei-ichi Nakayama

Primary Identifier  MGI:2179051 Allele Type  Targeted
Attribute String  Null/knockout Gene  Skp2
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 1-4 of this gene were replaced with a PGK-neo-poly(A) cassette via homologous recombination, resulting in the loss of the translation initiation site and F-box domain. RT-PCR verified gene expression was absent in homozygous mutant animals and immunoprecipitation failed to detect full length or truncated protein product.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Skp2-,
  • Skp2-,
  • Fbxl1<->,
  • Fbxl1<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

40 Publication categories

Trail: Allele