| Primary Identifier | MGI:2178433 | Allele Type | Chemically induced (ENU) |
| Gene | Tmem98 | Strain of Origin | (C3H/HeN x BALB/cAnN)F1 |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | Harwell ENU Mutagenesis |
| description | The Rwhs phenotype may not be fully penetrant and/or can be late onset, as 4 out of 22 mice were genotyped as carriers but did not exhibit a phenotype. |
| molecularNote | This phenotypic mutant was identified in an ENU mutagenesis screen. The molecular lesion is a T to C substitution in exon 5 of the gene (position 11:80,817,609 (GRCm38/mm10) Assembly). This mutation leads to the substitution of the nonpolar aliphatic amino acid, isoleucine, by the polar amino acid threonine (p.I135T) in the encoded protein. |
