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Allele : Brca1<tm1Rfo> breast cancer 1, early onset; targeted mutation 1, Ricardo Fodde

Primary Identifier  MGI:2178447 Allele Type  Targeted
Attribute String  Null/knockout Gene  Brca1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette was inserted into exon 20. RT-PCR analysis demonstrated that a mutant transcript was produced from this allele at normal expression levels. A truncated protein lacking the last BCRT repeat is predicted to be expressed from this allele.
  • mutations:
  • Insertion
  • synonyms:
  • Brca1(1700T),
  • Brca1(1700T)
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories