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Allele : Lama4<tm1Ktry> laminin, alpha 4; targeted mutation 1, Karl Tryggvason

Primary Identifier  MGI:2179127 Allele Type  Targeted
Attribute String  Null/knockout Gene  Lama4
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  The promoter region and exons 1 and 2 were replaced with a neomycin cassette via homologous recombination. Northern blot verified the absence of gene transcript in muscle and heart from homozygous mutant animals. Immunostaining of capillary basement membrane from homozygous mutants did not detect protein product.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Lama4<tm1Blp>,
  • Lama4<tm1Blp>,
  • Lama4-,
  • Lama4-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

34 Publication categories