| Primary Identifier | MGI:2179133 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Chrna6 |
| Transmission | Germline | Strain of Origin | 129S2/SvPas |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A 4 kb region of this gene including exons 1 and 2 was replaced with a neomycin cassette via homologous recombination, resulting in the deletion of sequences encoding the translation initiation codon, signal peptide, and part of the N-terminal extracellular domain. In situ hybridization did not detect mRNA in retinal ganglion cells from brain of homozygous mutant animals. |
