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Allele : Gata4<tm1Eno> GATA binding protein 4; targeted mutation 1, Eric N Olson

Primary Identifier	MGI:2179443	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Gata4
Transmission	Germline	Strain of Origin	129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase	false	Is Wild Type	false

molecularNote

Exons containing the 2 DNA-binding zinc finger domains were replaced with a neomycin cassette via homologous recombination. RT-PCR analysis of homozygous mutant embryos did not detect wild-type transcript.

mutations:
Intragenic deletion,
Insertion

cellLines:
Not Specified

synonyms:
GATA4-,
GATA4-

earliestPublication:
Molkentin JD, et al. (1997) Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis. Genes Dev 11(8):1061-1072

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

21 Publication categories

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