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Allele : Gsn<tm1Djk> gelsolin; targeted mutation 1, David J Kwiatkowski

Primary Identifier  MGI:2179509 Allele Type  Targeted
Attribute String  Null/knockout Gene  Gsn
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance cassette was inserted into the first coding exon, 60 bp downstream of the initiation codon. Northern blot analysis on RNA derived from various tissues of homozygous mice demonstrated that no transcript was produced from this allele. Activity assays and western blotting experiments confirmed that no functional protein was expressed.
  • mutations:
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

31 Publication categories