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Allele : Rph3a<tm1Sud> rabphilin 3A; targeted mutation 1, Thomas C Sudhof

Primary Identifier	MGI:2179730	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Rph3a
Transmission	Germline	Strain of Origin	129P2/OlaHsd
Is Recombinase	false	Is Wild Type	false

molecularNote

A neomycin resistance cassette replaced two exons encoding residues 74-146 of the encoded protein. Western blot analysis on brain tissues of homozygous mice confirmed that no encoded protein was detected.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
rabphilin KO,
rabphilin KO

earliestPublication:
Schluter OM, et al. (1999) Rabphilin knock-out mice reveal that rabphilin is not required for rab3 function in regulating neurotransmitter release. J Neurosci 19(14):5834-46

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

9 Publication categories

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