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Allele : Sv2a<tm1Baj> synaptic vesicle glycoprotein 2a; targeted mutation 1, Sandra M Bajjalieh

Primary Identifier	MGI:2179735	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Sv2a
Transmission	Germline	Strain of Origin	129
Is Recombinase	false	Is Wild Type	false

molecularNote

A neomycin resistance gene replaced a genomic fragment including the exon containing the translation initiation codon. Western blot analysis on brain extracts derived from homozygous mice confirmed that no detectable encoded protein was present.

mutations:
Intragenic deletion,
Insertion

cellLines:
Not Specified

earliestPublication:
Crowder KM, et al. (1999) Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A). Proc Natl Acad Sci U S A 96(26):15268-73

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

2 Carried By

0 Driven By

12 Publication categories

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