|  Help  |  About  |  Contact Us

Allele : Cacna1d<tm1Jst> calcium channel, voltage-dependent, L type, alpha 1D subunit; targeted mutation 1, Jorg Striessnig

Primary Identifier  MGI:2180141 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cacna1d
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
description  Phenotypic Similarity to Human Syndrome: Sick Sinus Syndrome J: 230439.
molecularNote  Exon 2 was disrupted by insertion of a PGK-neo cassette via homologous recombination resulting in the introduction of multiple stop codons and translation termination before the first transmembrane domain. Absence of gene expression was verified by Western blot analysis of brain membrane protein from homozygous mutant animals.
  • mutations:
  • Insertion
  • synonyms:
  • Cav1.3alpha1<->,
  • Cav1.3<->,
  • Cav1.3<->,
  • Cav1.3alpha1<->,
  • alpha1D-,
  • alpha1D-
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

54 Publication categories