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Allele : Syt1<tm2Sud> synaptotagmin I; targeted mutation 2, Thomas C Sudhof

Primary Identifier  MGI:2180146 Allele Type  Targeted
Gene  Syt1 Transmission  Germline
Strain of Origin  129P2/OlaHsd Is Recombinase  false
Is Wild Type  false
molecularNote  A neomycin resistance cassette was inserted into intron 1 via homologous recombination and results in a normal protein product. Western blot of brain homogenates from homozygous mutant animals verified the presence of protein expression and enzyme assays demonstrated that the phospholipid- and syntaxin-binding ability of the protein remained intact.
  • mutations:
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories