| Primary Identifier | MGI:2180153 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Cacng1 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The 3' portion of exon 1 and adjacent splice donor site were replaced with a neo resistance cassette via homologous recombination. Absence of gene expression was confirmed by Northern and Western blot analysis of skeletal muscle from homozygous mutant animals. In addition, RT-PCR failed to amplify the complete coding region of the gene as well as portions of the transcript corresponding to exons 2, 3, and 4. |
