| Primary Identifier | MGI:2179689 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Nfkb2 |
| Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The carboxy terminal domain of the protein was disrupted by insertion of a termination codon at position 451 and the replacement of the sequences encoding residues 451 to 690 with a neomycin resistance cassette. Immunoprecipitation analysis on lysates of stimulated thymocytes demonstrated that the larger precursor protein was not made, but a processed and truncated p52 protein was present. |