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Allele : Tnfrsf11b<tm1Eac> tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin); targeted mutation 1, Edward A Clark

Primary Identifier  MGI:2179712 Allele Type  Targeted
Attribute String  Null/knockout Gene  Tnfrsf11b
Transmission  Germline Strain of Origin  129S4/SvJaeSor
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance gene replaced a genomic fragment containing sequences encoding part of the signal peptide, the first two cysteine rich repeats and part of the third cysteine rich repeat. Northern blot analysis on total RNA derived from liver of homozygous mice demonstrated that a smaller transcript was expressed from this allele, but it is predicted to produce a nonfucntional protein.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • opg -,
  • opg -
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

19 Publication categories