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Allele : Xrcc6<tm1Fwa> X-ray repair complementing defective repair in Chinese hamster cells 6; targeted mutation 1, Frederick W Alt

Primary Identifier  MGI:2179954 Allele Type  Targeted
Attribute String  Null/knockout Gene  Xrcc6
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  450 bp of this gene encompassing exon 4 and part of exon 5 were replaced with a neo cassette via homologous recombination resulting in a shift in the reading frame and predicted protein truncation after the first 64 residues. Homozygous mutant ES cells were identified by Southern blot analysis and Western blot analysis confirmed the absence of protein product.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Ku70-,
  • Ku70DKO,
  • Ku70-,
  • Ku70DKO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

39 Publication categories