Primary Identifier | MGI:2179987 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Xrcc5 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | 6 kb of this gene encoding amino acids 229-313 were replaced with a PGK-puro cassette via homologous recombination resulting in a frameshift after residue 313 and deleting 69% of the protein product. Northern blot analysis and RT-PCR of embryonic fibroblasts from homozygous mutants did not detect gene transcript. |