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Allele : Xrcc5<tm1Dbr> X-ray repair complementing defective repair in Chinese hamster cells 5; targeted mutation 1, David B Roth

Primary Identifier  MGI:2179987 Allele Type  Targeted
Attribute String  Null/knockout Gene  Xrcc5
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  6 kb of this gene encoding amino acids 229-313 were replaced with a PGK-puro cassette via homologous recombination resulting in a frameshift after residue 313 and deleting 69% of the protein product. Northern blot analysis and RT-PCR of embryonic fibroblasts from homozygous mutants did not detect gene transcript.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Ku80-,
  • xrcc5-,
  • xrcc5-,
  • Ku86-,
  • xrcc5<M1>,
  • xrcc5<M1>,
  • Ku80-,
  • Ku86-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

28 Publication categories