Primary Identifier | MGI:2179998 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Arhgap5 |
Transmission | Germline | Strain of Origin | 129S2/SvPas |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A PGK-neo cassette is inserted in reverse transcriptional orientation relative to the coding sequence, disrupting the gene immediately upstream of the GTPase domain. Immunoblot of embryonic tissue probed with antisera failed to detect protein in homozygous mutant animals. |