| Primary Identifier | MGI:2180180 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Araf |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A neomycin selection cassette replaced a region encoding the cysteine finger of the CR1 domain, the entire CR2 domain, and the ATP-binding site of the CR3 domain. Western blot analysis of embryonic fibroblasts derived from hemizygous mice indicated an absence of protein encoded by the targeted locis and showed normal levels of protein produced by an adjacent locus. |
