First Author | Wehrli S | Year | 2007 |
Journal | Mol Genet Metab | Volume | 91 |
Issue | 2 | Pages | 191-4 |
PubMed ID | 17433749 | Mgi Jnum | J:122348 |
Mgi Id | MGI:3714101 | Doi | 10.1016/j.ymgme.2007.02.013 |
Citation | Wehrli S, et al. (2007) Evidence for function of UDP galactose pyrophosphorylase in mice with absent galactose-1-phosphate uridyltransferase. Mol Genet Metab 91(2):191-4 |
abstractText | Mice with deletion of the galactose-1-phosphate uridyltransferase (GALT) gene were examined for their ability to form (13)C labeled hepatic UDP glucose from administered 1-(13)C galactose. NMR analysis of urinary acetaminophen glucuronide, which is derived from hepatic UDP glucose showed (13)C enrichment after concomitant administration of (13)C galactose and acetaminophen. The finding is consistent with the function of UDP galactose pyrophosphorylase as an alternate pathway of galactose metabolism. |