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Allele : Bmal1<tm1Bra> basic helix-loop-helix ARNT like 1; targeted mutation 1, Christopher A Bradfield

Primary Identifier  MGI:2180361 Allele Type  Targeted
Attribute String  Null/knockout Gene  Bmal1
Transmission  Germline Strain of Origin  129/Sv
Is Recombinase  false Is Wild Type  false
molecularNote  A portion of exon 4 containing the helix-loop-helix coding domain and all of exon 5 were replaced by a neomycin selection cassette. A larger transcript, resulting from a cryptic splice site between exon 3 and the neomycin resistance gene, was detected by Northern blot analysis. The polypeptide truncates 15 residues after this splice site, prior to the functional domains encoded by exon 4 in the wild-type locus.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Bmal1-KO,
  • mMop3<->,
  • bmal1-,
  • Bmal1-KO,
  • Mop3<->,
  • mMop3<->,
  • Mop3<->,
  • bmal1-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

155 Publication categories