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Allele : Cav1<tm1Mls> caveolin 1, caveolae protein; targeted mutation 1, Michael P Lisanti

Primary Identifier  MGI:2180364 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cav1
Transmission  Germline Strain of Origin  STOCK 129/Sv and C57BL/6J and SJL
Is Recombinase  false Is Wild Type  false
molecularNote  A 2.2 kb region of the gene including exons 1 and 2 and part of the promoter region was replaced with a neo resistance cassette via homologous recombination. Absence of gene expression in homozygous mutant animals was verified by Western blot analysis of heart, adipose, and lung tissue, and also of mouse embryonic fibroblasts cultured from E13.5 homozygous mutant embryos.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Cav-1 KO,
  • Cav-1 KO,
  • Cav-1-,
  • Caveolin-1 KO,
  • Caveolin-1 KO,
  • Cav-1-,
  • cav<->,
  • Cav<tm1Mls>,
  • cav<->,
  • Cav<tm1Mls>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

4 Carried By

0 Driven By

309 Publication categories