| Primary Identifier | MGI:2180750 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Igdcc3 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The gene was disrupted by insertion of a PGK-neo-lacZ cassette into exon 2 via homologous recombination, which introduces stop codons into all 3 reading frames. LoxP sites flank the PGK-neo portion of the targeting vector. Northern blot analysis of E11.5 homozygous mutant embryos did not detect gene transcripts. RT-PCR detected very low amounts of mutant transcripts thought to originate within the lacZ gene. |
