| Primary Identifier | MGI:2180054 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Abcb1a |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A 1.6-kb fragment containing exons 6 and 7 and encoding the extracellular, transmembrane, and cytoplasmic domains, was replaced by the insertion of a hygromycin cassette. While low levels of transcript were detected in the intestines of homozygous mutant mice by RNAase protection assays, immunoblot analysis showed an absence of protein expression. |
