Primary Identifier | MGI:2180102 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Adh7 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A PGK-neo cassette replaced the promoter and exons 1 through 6. Northern blot analysis showed an absence of transcript in extracts isolated from the stomach and skin tissue of homozygous mutant mice. Western blot analysis confirmed a lack of encoded protein and normal levels of other alcohol dehydrogenases in homozygous mutant animals. |