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Allele : Adh7<tm1Gdu> alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide; targeted mutation 1, Gregg Duester

Primary Identifier  MGI:2180102 Allele Type  Targeted
Attribute String  Null/knockout Gene  Adh7
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A PGK-neo cassette replaced the promoter and exons 1 through 6. Northern blot analysis showed an absence of transcript in extracts isolated from the stomach and skin tissue of homozygous mutant mice. Western blot analysis confirmed a lack of encoded protein and normal levels of other alcohol dehydrogenases in homozygous mutant animals.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Adh4<->,
  • Adh4<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

10 Publication categories

Trail: Allele