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Allele : Defb1<tm1Jmw> defensin beta 1; targeted mutation 1, James M Wilson

Primary Identifier  MGI:2180305 Allele Type  Targeted
Attribute String  Null/knockout Gene  Defb1
Transmission  Germline Strain of Origin  129S5/SvEvBrd
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 1 was replaced with a neomycin resistance gene via homologous recombination. Gene expression is absent in kidneys and trachea of homozygous mutant animals as determined by Northern blot analysis, RNase protection assay, and RT-PCR.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • mBD-1-,
  • mBD-1-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

6 Publication categories