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Allele : Ckmt2<tm1Bew> creatine kinase, mitochondrial 2; targeted mutation 1, Be Wieringa

Primary Identifier  MGI:2180507 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ckmt2
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  400 bp of the gene including part of exon 2, exon 3, and the translation initiation codon was replaced with a hygromycin resistance cassette via homologous recombination. Northern blot analysis detected mutant transcripts in cardiac and skeletal muscle of homozygous mutant animals, but Western blot analysis of the same tissues demonstrated the absence of protein product.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • ScCKmit-,
  • ScCKmit-,
  • Mib-CK-,
  • Mito-CK<->,
  • MtCK<->,
  • Mito-CK<->,
  • MtCK<->,
  • Mib-CK-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

25 Publication categories