Primary Identifier | MGI:2180711 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Cd1d1 |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A neomycin selection cassette replaced 200 nucleotides in exon 3 of Cd1d1, while leaving the adjacent Cd1d2 locus intact. Thymocytes derived from homozygous mutant mice were shown to lack protein surface expression. This finding was confirmed by the inability of a specific hybridoma to recognize thymocytes from homozygous mutant mice. |