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Allele : Cdc25c<tm1Hpw> cell division cycle 25C; targeted mutation 1, Helen Piwnica-Worms

Primary Identifier  MGI:2180791 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cdc25c
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 3 was disrupted by the insertion of a neomycin resistance gene. Northern blot analysis of total testicular RNA showed the exclusive presence of a longer transcript, containing the neo transgene, in extracts from homozygous mutant mice. Western blot analysis of MEF lysates derived from homozygous mutant animals showed an absence of encoded protein using various antibodies.
  • mutations:
  • Insertion
  • synonyms:
  • Cdc25C<->,
  • Cdc25C<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

9 Publication categories