| Primary Identifier | MGI:2180780 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Cdc45 |
| Transmission | Germline | Strain of Origin | 129S4/SvJae |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A neomycin selection gene replaced exons 1 and 2, which encode the 199 amino-terminal residues. RT-PCR analysis of total RNA obtained from heterozygous mutant embryos showed that the level of normal transcript was approximately half of what was detected in wild-type embryos. |